I had been in terrible knee pain due to no cartilage left in right knee. It became bone on bone. Dr. Gerber said the gel might really help me. Stephanie was great and shots didn't hurt at all . They worked so well I just came back after 2 years to get them again. I lost 50 pounds because they said one pound lost is 6 lbs. on your knee. I'm actually dancing out of the office now and plan on playing ice hockey again!